Overview
Antidepressants are drugs used to treat major depressive disorders, anxiety disorders, and other mental illnesses. They work by altering the balance of neurotransmitters – chemicals in the brain that regulate mood and emotions. In particular, antidepressants affect the levels of serotonin, norepinephrine, and dopamine in the brain. The three main types of antidepressants are selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs). SSRIs are the most commonly prescribed type of antidepressant. They work by blocking the reuptake of serotonin, which increases its availability in the brain. This leads to improved mood and reduced anxiety. SNRIs work similarly but also block the reuptake of norepinephrine. TCAs are an older type of antidepressant that is not used as frequently due to their side effects. They work by blocking the reuptake of serotonin and norepinephrine, as well as dopamine in some cases. In addition to treating major depressive disorders and anxiety disorders, antidepressants may also be used to treat chronic pain, bipolar disorder, and other conditions. They are generally safe and effective but can have side effects such as nausea, dizziness, and sexual dysfunction. It’s important to talk to a healthcare provider about the benefits and risks of antidepressant therapy and to follow their instructions for use.
Research published in this journal
2 peer-reviewed articles, ranked by relevance. Each links to its DOI.
A New Spectrofluorimetric Approach for The Quantitation of Imipramine Hcl in Commercial Dosage Forms
How this research is being cited
The 2 articles above have been cited 6 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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Yaver Subasi et al. · 2022 · Chemické zvesti
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Syed Najmul Hejaz Azmi et al. · 2022 · Journal of King Saud University - Science
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2022 · Journal of King Saud University - Science
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2022 · Chemical Papers
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2018 · Journal of new developments in Chemistry
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2018 · Journal of new developments in Chemistry
A sample of recent works citing this journal's research on Antidepressant Drug Therapy, linking to each citing work.