Research Topic · Peer-Reviewed

Rodents

Rodents are a diverse order of mammals distinguished by a single pair of continuously growing incisors in each jaw, adapted for gnawing. In pharmaceutical and biomedical science they are the predominant laboratory animal models, with rats and mice used extensively to study disease mechanisms and to evaluate the effi…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 80× across the literature 🔖 ISSN 2328-0182 🗓 Reviewed July 2026

Overview

Rodents are a diverse order of mammals distinguished by a single pair of continuously growing incisors in each jaw, adapted for gnawing. In pharmaceutical and biomedical science they are the predominant laboratory animal models, with rats and mice used extensively to study disease mechanisms and to evaluate the efficacy, pharmacology, and toxicology of candidate therapeutics before human testing. Their value derives from physiological and genetic similarities to humans, short generation times, and the availability of well-characterised and genetically modified strains, which allow controlled investigation of drug effects, metabolic and endocrine regulation, and organ-level pathology. Research using rodent models in this area includes acute and subacute toxicity evaluation of plant extracts, studies of dietary manipulation on tumour growth, adiposity, and skeletal-muscle adaptation, neuroendocrine and metabolic experiments such as catecholamine secretion in obesity models, and behavioural and physiological work on fear, anxiety, and pain signalling. Such models support dose-finding, safety assessment, and mechanistic understanding across therapeutic areas. Rodent research matters because it provides an experimentally tractable system that bridges molecular findings and clinical translation, within established ethical and regulatory frameworks. The journal publishes peer-reviewed research employing rodent and other animal models to investigate pharmacological, nutritional, and pathophysiological questions.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2015

Epigenetics and Nutrition

Lundstrom KennethCorresponding author
PanTherapeuitcs, Rue des Remparts 4, CH1095 Lutry, Switzerland
Exact topic International Journal of Nutrition Cited by 2 doi:10.14302/issn.2379-7835.ijn-14-603

How this research is being cited

The 12 articles above have been cited 80 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Rodents, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Advanced Pharmaceutical Science And Technology (ISSN 2328-0182).

Journal editorial board
natalia malara · Italy Saba Khalilpour · Italy Haseeb Khan · United States

This page summarises published research for orientation; it is not medical or professional advice.