Research Topic · Peer-Reviewed

Clinical Trials

Clinical trials are prospective research studies in which interventions, such as drugs, biologics, devices, or treatment strategies, are evaluated in human participants to determine their safety, efficacy, and optimal use. They are conducted in sequential phases that progress from initial assessment of safety and do…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 14× across the literature 🗓 Reviewed July 2026

Overview

Clinical trials are prospective research studies in which interventions, such as drugs, biologics, devices, or treatment strategies, are evaluated in human participants to determine their safety, efficacy, and optimal use. They are conducted in sequential phases that progress from initial assessment of safety and dosing to larger comparisons of effectiveness and monitoring of longer-term outcomes, and they provide the rigorous evidence required before a new therapy can be adopted in practice. Methodological safeguards distinguish trials from observational research, most importantly randomization to reduce allocation bias and blinding to limit the influence of expectation on assessment, techniques whose careful application has a long history in therapeutic research. The field spans diverse therapeutic areas, including vaccine development, oncology and targeted antibody therapy, cell-based treatments, and the evaluation of nutritional and plant-derived interventions, as well as the systematic assessment of toxicology and drug safety. Trials generate quantitative measures of benefit and harm through predefined endpoints, often synthesized across studies in meta-analyses. They also address why candidate treatments must be tested in humans before marketing, given that preclinical models cannot fully predict clinical response. Underpinned by ethical principles and regulatory oversight, clinical trials are the central mechanism by which medical innovations are validated and translated into improved patient care.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 14 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Clinical Trials, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Advanced Therapeutic Science.

Journal editorial board
Ruman Rahman · United Kingdom Dong-Kug Choi · South Korea

This page summarises published research for orientation; it is not medical or professional advice.