Research Topic · Peer-Reviewed

Cellular Senescence

Cellular senescence is a state in which a cell permanently stops dividing while remaining metabolically active, entering a stable form of growth arrest rather than dying. It is triggered by stresses such as telomere shortening, DNA damage, and oncogene activation, and it serves as a protective brake that can prevent…

Curated from this journal's research 📚 11 peer-reviewed articles cited Cited 34× across the literature 🔖 ISSN 2474-7785 🗓 Reviewed July 2026

Overview

Cellular senescence is a state in which a cell permanently stops dividing while remaining metabolically active, entering a stable form of growth arrest rather than dying. It is triggered by stresses such as telomere shortening, DNA damage, and oncogene activation, and it serves as a protective brake that can prevent damaged cells from becoming cancerous. Over a lifetime, however, senescent cells accumulate in tissues and secrete inflammatory factors, a process linked to aging and to many age-related conditions. Within the broad scope of Aging Research And Healthcare, senescence connects to several lines of inquiry represented in the journal's archive. Work on oxidative telomere attrition and nutritional antioxidants examines how oxidative stress and telomere maintenance influence biological aging, a core driver of the senescent state. Studies evaluating SIRT1 and telomerase activity address molecular pathways closely tied to cellular lifespan and anti-aging mechanisms, while research on frailty and the immune system explores how aging at the cellular and systemic level shapes resilience in older adults. This page gathers peer-reviewed, open-access research relevant to cellular senescence and the biology of aging.

Research published in this journal

11 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2017

Frailty and the Immune System

Wilson DaisyCorresponding author
Institute of Ageing and Inflammation, University of Birmingham, Edgbaston, Birmingham, UK, B15 2GW
Exact topic Aging Research And Healthcare Cited by 19 doi:10.14302/issn.2474-7785.jarh-17-1578
2019

Robust Sampling of Defective Pathways in Parkinson Disease

Luis Fernández-Martínez JuanCorresponding author
Group of Inverse Problems, Optimization and Machine Learning. Department of Mathematics. C/ Federico García Lorca, 18. 33007 Oviedo. University of Oviedo. Spain
Exact topic Medical Informatics and Decision Making Cited by 2 doi:10.14302/issn.2641-5526.jmid-18-2529

How this research is being cited

The 11 articles above have been cited 34 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Cellular Senescence, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Aging Research And Healthcare (ISSN 2474-7785).

Journal editorial board
Anna Aiello · Italy Juan Manuel Carmona Torres · Spain IAN JAMES MARTINS · Australia

This page summarises published research for orientation; it is not medical or professional advice.