Research Topic · Peer-Reviewed

Lymphoma

Lymphoma is a malignant neoplasm of the lymphatic system arising from the clonal proliferation of lymphocytes, most often within lymph nodes but also in extranodal sites such as the central nervous system, skin, bone, breast implant capsules, and the external auditory canal. It is broadly divided into Hodgkin lympho…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 28× across the literature 🗓 Reviewed October 2026

Overview

Lymphoma is a malignant neoplasm of the lymphatic system arising from the clonal proliferation of lymphocytes, most often within lymph nodes but also in extranodal sites such as the central nervous system, skin, bone, breast implant capsules, and the external auditory canal. It is broadly divided into Hodgkin lymphoma, defined histologically by Reed-Sternberg cells and including nodular lymphocyte-predominant and classical subtypes, and the heterogeneous non-Hodgkin lymphomas, which span indolent and aggressive B-cell, T-cell, and NK-cell entities. Recognized variants include MALT (mucosa-associated lymphoid tissue) lymphoma, lymphoepithelioid (Lennert) lymphoma, anaplastic large cell lymphoma, and post-transplant lymphoproliferative disorders driven by immunosuppression. Diagnosis integrates tissue histopathology, immunophenotyping, and cytology, with fine-needle aspiration helping triage lymphoid lesions, while biochemical indices such as lactate dehydrogenase can reflect disease burden. Clinical behavior ranges from localized disease to widespread infiltration, and management commonly employs combination chemotherapy regimens such as R-CHOP, sometimes complicated by opportunistic infection or paraneoplastic phenomena. Sub-type distribution and treatment outcomes vary substantially across age groups and between well-resourced and resource-limited settings, making accurate classification central to prognosis and therapy selection.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 28 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Lymphoma, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Bone Marrow Biology.

Journal editorial board
Azad Saei · Sweden Sadanand Fulzele · United States Shanmuganathan Chandrakasan · United States

This page summarises published research for orientation; it is not medical or professional advice.