Overview
Molecular biomarkers are measurable molecules, including DNA, RNA, proteins, and metabolites, whose detection or quantification reflects a specific biological or pathological process and so serves as an indicator of health, disease, or response to intervention. They operate at the molecular level to reveal the presence or progression of a condition, often before clinical signs appear, and to support diagnosis, prognosis, and the monitoring of treatment. Classified by molecule type and by clinical use, they include diagnostic, prognostic, predictive, and pharmacodynamic markers identified through genomic, transcriptomic, proteomic, and metabolomic analysis. In cancer research, molecular biomarkers underpin diagnostics and personalised medicine, with proteomic and genomic techniques applied across cancer detection and treatment, and with epigenetic markers and circulating microRNAs contributing to risk assessment and disease tracking. Their value increases when combined with other diagnostic tools to improve accuracy across a wide range of diseases, and their development depends on rigorous validation to ensure reliability. Significance lies in enabling earlier detection and more precisely targeted, individualised care. Principal sub-areas include nucleic-acid, protein, and metabolite markers, epigenetic biomarkers, circulating and microRNA-based markers, and the analytical and validation strategies that translate molecular measurements into clinically useful tests.
Research published in this journal
7 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Developing Cellular & Molecular Biomarkers for Anti-Inflammatory Activities of Probiotic Bacteria in Fermented Foods
Epigenetic Biomarkers in Head and Neck Cancer
Proteomic and Genomic Techniques in Medical Research: Applications in Cancer, Diagnostics, and Personalized Medicine
High-Throughput Complex Disease Modeling for Ethical Drug Discovery: Clinical Relevance of a NAM Platform for Cancer Biomarker Development
The Current Immunoassays and Emerging Immunogenomic Approaches for Immunomonitoring Cancer and Infectious Diseases
Dynamic MicroRNA-Expression in Plasma of Melanoma Patients Correlates With Progression, PD-L1 Status and Overall Survival
How this research is being cited
The 7 articles above have been cited 16 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
-
2026 · Human Gene
-
Maria Constantin et al. · 2024 · Frontiers in Oncology
-
2024 · Biomedical Research and Therapy
-
2023 · Medical Oncology
-
S. Kurevlev et al. · 2023 · Head and Neck Tumors (HNT)
-
2023 · Medical Oncology
-
2023 · Head and neck tumors (HNT)
-
2023 ·
A sample of recent works citing this journal's research on Molecular Biomarkers, linking to each citing work.