Overview
In clinical medicine the abbreviation ART most often denotes antiretroviral therapy, the combination drug treatment that suppresses replication of the human immunodeficiency virus. By combining agents from different classes that act at distinct points of the viral life cycle, antiretroviral therapy reduces plasma viral load, restores and preserves immune function as reflected in CD4 cell counts, prevents progression to AIDS, and markedly lowers the risk of onward transmission. Effective therapy depends on sustained adherence, management of drug resistance and adverse reactions, and attention to comorbidity, including cardiovascular risk, peripheral neuropathy, frailty, and respiratory disease, as well as the psychosocial and structural factors that shape engagement with care across diverse settings. The field also addresses resistance monitoring, simplified and two-drug regimens, treatment in children and adolescents, disclosure, and long-term health outcomes in people living with HIV. The peer-reviewed research collected under this topic addresses drug resistance and adherence among people on antiretroviral therapy, long-term health and disability outcomes, cardiovascular and frailty markers, regimen characterisation, and the psychosocial determinants of treatment success, reflecting the breadth of antiretroviral therapy as a discipline spanning virology, immunology, pharmacology, and the behavioural and health-systems dimensions of managing a chronic, treatable infection across the lifespan and in varied populations.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Disability and Health Outcomes – From a Cohort of People on Long Term ART
The Psychosocial Factors that Influencing Antiretroviral Treatment Adherence
Prevalence and Factors Associated with Disclosure of HIV Diagnosis to Infected Children Receiving Antiretroviral Treatment in Public Health Care Facilities in Gauteng, South Africa
Cardiovascular Risk Factors Among People Being Treated for HIV in Nepal: A Cross-Sectional Study
When and How Should we be Measuring Adherence to Antiretroviral Therapy in Resource-Limited Settings?
A Cross Sectional Analysis of Frailty and Markers of Frailty in Young People Living with HIV/AIDS
Characterization of People Receiving 2-Drug Regimens (2DR) for HIV Management in Italy
Spirometric profile of people living with HIV on antiretroviral drugs in Abidjan
Prevalence and Risk Factors of HIV Infection among Children Born from HIV Positive Women Musanze District, Rwanda
How this research is being cited
The 12 articles above have been cited 30 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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J. E. Tawiah et al. · 2025 · AIDS Care
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2025 · AIDS Care
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2025 · Virology Journal
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Doreen Kamori et al. · 2024 · PLoS ONE
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2024 · PLoS ONE
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2024 · Heliyon
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2024 · Heliyon
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Wondmneh Yoseph et al. · 2024 · International Archives of Nursing and Health Care
A sample of recent works citing this journal's research on Art, linking to each citing work.