Overview
Cancer immunotherapy is a class of treatment that harnesses or modifies the immune system to recognize and destroy malignant cells, exploiting the immune system's capacity for specificity and memory to target tumours. It encompasses several major modalities, including immune-checkpoint inhibition that releases brakes on T-cell responses, adoptive cell therapies such as chimeric antigen receptor (CAR) T cells engineered to recognize tumour antigens, therapeutic and antigen-based vaccination, cytokine therapy, and antibody-based approaches. Advances at the interface of nanotechnology and immunotherapy seek to improve the delivery, targeting, and efficacy of cellular and molecular agents, extending the reach of CAR-T-cell and related technologies. Effective immunotherapy depends on understanding tumour antigens and the immune microenvironment, including oncofoetal antigens such as alpha-fetoprotein and its receptor, which inform both targeting and diagnosis. Immunomonitoring is integral to the field, with immunoassays and emerging immunogenomic approaches used to characterize antitumour immune responses, track treatment effect, and guide patient selection across cancer and infectious disease. Immunotherapy is applied across diverse malignancies and is increasingly integrated with surgery, chemotherapy, and other modalities, although its use does not uniformly alter the extent of other interventions. By directing immune effectors against cancer cells and enabling durable responses in some patients, cancer immunotherapy represents a distinct and rapidly developing therapeutic strategy, supported by advances in molecular targeting, delivery, and immunological monitoring.
Research published in this journal
7 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Avant Garde Alleviation -Cancer Immunotherapy
The Current Immunoassays and Emerging Immunogenomic Approaches for Immunomonitoring Cancer and Infectious Diseases
Nanotechnology Meets Immunotherapy: CAR-T Cells Technology and Beyond
Alpha-Fetoprotein and its Receptor: More Than Oncofoetal Antigens.
Molecular Diagnosis in Clinical Management and Diagnosis of Thyroid Cancer
Challenger and Propose Novel Methods and Techniques for Prevention, Prognosis, Diagnosis, Imaging, Screening, Treatment and Management of Lung Cancer
How this research is being cited
The 7 articles above have been cited 6 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2024 · Journal of Environmental Pathology, Toxicology and Oncology
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2023 · Journal of Environmental Pathology Toxicology and Oncology
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CFTR-mediated monocyte/macrophage dysfunction revealed by cystic fibrosis proband-parent comparisons2022 · JCI Insight
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CFTR-mediated monocyte/macrophage dysfunction revealed by cystic fibrosis proband-parent comparisons2022 · JCI Insight
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2021 · medRxiv (Cold Spring Harbor Laboratory)
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CFTR-mediated monocyte-macrophage dysfunction revealed by cystic fibrosis proband-parent comparisonsX. Zhang et al. · 2021 · medRxiv
A sample of recent works citing this journal's research on Immunotherapy of Cancer, linking to each citing work.