Research Topic · Peer-Reviewed

Mice

Mice, principally the species Mus musculus, are the most widely used mammalian model organism in biomedical research, valued for their small size, rapid breeding, fully sequenced genome, and extensive genetic toolkit. Inbred strains, transgenic and knockout lines, and humanized models allow precise manipulation of s…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 42× across the literature 🔖 ISSN 2694-2275 🗓 Reviewed July 2026

Overview

Mice, principally the species Mus musculus, are the most widely used mammalian model organism in biomedical research, valued for their small size, rapid breeding, fully sequenced genome, and extensive genetic toolkit. Inbred strains, transgenic and knockout lines, and humanized models allow precise manipulation of single genes and pathways, making the mouse central to genetics, immunology, oncology, and toxicology. Their physiological and immunological similarity to humans supports the modelling of disease and the testing of therapeutic and toxic agents, while standardized husbandry yields reproducible results. Research relevant to this area includes anti-inflammatory effects of black cumin and honey in Mus musculus, strain-specific proteomic differences in transgenic mice expressing human surfactant proteins, learning and memory in long-lived Ames dwarf mice, tumour development in p53-knockout mice, and the hepatoprotective and neuroprotective effects of compounds such as quercetin against rotenone-, manganese-, and dichlorvos-induced toxicity. Studies of dietary fish oil and breast carcinoma growth, and of immunoglobulin responses, further illustrate the model's reach across metabolism, neuroscience, and immunology. The journal publishes peer-reviewed research using mouse models across experimental zoology, toxicology, oncology, and physiology, including genetically modified strains that dissect gene function and disease mechanisms.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 42 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Mice, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Zoological Research (ISSN 2694-2275).

Journal editorial board
Alexander Ereskovsky · France ANDREI ALIMOV · Russia

This page summarises published research for orientation; it is not medical or professional advice.